Fluoride Release from Glass Ionomer Cements Correlates with the Necrotic Death of Human Dental Pulp Stem Cells
نویسندگان
چکیده
Glass ionomer cements (GICs) are commonly used as restorative materials. Th e eff ect of GICs on diff erent cell types varies. Stem cells from Human Exfoliated Deciduous teeth, SHED are a source for dental tissue regeneration. Th e necrosis and infl ammation that eventually follows necrosis can disturb this regenerative process. We tested seven GICs including Fuji I, Fuji II, Fuji VIII, Fuji IX, Fuji plus, Fuji triage and Vitrebond for their necrotic induction potential in human SHEDs. We also correlated these eff ects with eluate fl uoride release. Th e toxicity of GICs was tested via a lactate dehydrogenase assay and fl ow cytoReceived / Primljen: 03. 05. 2011. Accepted / Prihvaćen: 06. 06. 2011.
منابع مشابه
Cytotoxic effects of glass ionomer cements on human dental pulp stem cells correlate with fluoride release.
OBJECTIVES Glass ionomer cements (GICs) are commonly used as restorative materials. Responses to GICs differ among cell types and it is therefore of importance to thoroughly investigate the influence of these restorative materials on pulp stem cells that are potential source for dental tissue regeneration. Eight biomaterials were tested: Fuji I, Fuji II, Fuji VIII, Fuji IX, Fuji Plus, Fuji Tria...
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